Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine

<p>Abstract</p> <p>Background</p> <p>Extensive genetic diversity in vaccine antigens may contribute to the lack of efficacy of blood stage malaria vaccines. Apical membrane antigen-1 (AMA1) is a leading blood stage malaria vaccine candidate with extreme diversity, poten...

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Bibliographic Details
Main Authors: Ellis Ruth D, Duan Junhui, Niangaly Amadou, Dicko Alassane, Sagara Issaka, Saye Renion, Takala-Harrison Shannon, Mu Jianbing, Ouattara Amed, Miller Louis H, Su Xin-zhuan, Plowe Christopher V, Doumbo Ogobara K
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/9/1/175