RNA-mediated epigenetic heredity requires the cytosine methyltransferase Dnmt2.

RNA-mediated epigenetic heredity requires the cytosine methyltransferase Dnmt2.

RNA-mediated transmission of phenotypes is an important way to explain non-Mendelian heredity. We have previously shown that small non-coding RNAs can induce hereditary epigenetic variations in mice and act as the transgenerational signalling molecules. Two prominent examples for these paramutations...

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Bibliographic Details
Main Authors: Jafar Kiani, Valérie Grandjean, Reinhard Liebers, Francesca Tuorto, Hossein Ghanbarian, Frank Lyko, François Cuzin, Minoo Rassoulzadegan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3662642?pdf=render

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http://europepmc.org/articles/PMC3662642?pdf=render

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