Direct measurement of conformational strain energy in protofilaments curling outward from disassembling microtubule tips

Disassembling microtubules can generate movement independently of motor enzymes, especially at kinetochores where they drive chromosome motility. A popular explanation is the ‘conformational wave’ model, in which protofilaments pull on the kinetochore as they curl outward from a disassembling tip. B...

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Bibliographic Details
Main Authors: Jonathan W Driver, Elisabeth A Geyer, Megan E Bailey, Luke M Rice, Charles L Asbury
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/28433