Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis

Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis

Ovarian cancer is a highly lethal and the second highest in mortality among gynecological cancers. Stem cells either naïve or engineered are reported to inhibit various human cancers in both in-vitro and in-vivo. Herein we report the cancer inhibitory properties of human Wharton's jelly stem ce...

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Bibliographic Details
Main Authors: Gauthaman Kalamegam, Khalid Hussein Wali Sait, Farid Ahmed, Roaa Kadam, Peter Natesan Pushparaj, Nisreen Anfinan, Mahmood Rasool, Mohammad Sarwar Jamal, Muhammed Abu-Elmagd, Mohammed Al-Qahtani
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Oncology
Subjects:
stem cells
cancer stem cells
cell cycle
cell migration
tumor spheres
gene expression
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00592/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00592/full

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