Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjögren's Syndrome

Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjögren's Syndrome

Objectives: To perform a cross-comparative analysis of DNA methylation in patients with systemic lupus erythematosus (SLE), patients with primary Sjögren's syndrome (pSS), and healthy controls addressing the question of epigenetic sharing and aiming to detect disease-specific alterations.Method...

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Bibliographic Details
Main Authors: Juliana Imgenberg-Kreuz, Jonas Carlsson Almlöf, Dag Leonard, Christopher Sjöwall, Ann-Christine Syvänen, Lars Rönnblom, Johanna K. Sandling, Gunnel Nordmark
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
primary Sjögren's syndrome
DNA methylation
EWAS
epigenetics
autoimmunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01686/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01686/full

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