Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity.

Plasmodium falciparum sporozoites that develop and mature inside an Anopheles mosquito initiate a malaria infection in humans. Here we report the first proteomic comparison of different parasite stages from the mosquito -- early and late oocysts containing midgut sporozoites, and the mature, infecti...

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Bibliographic Details
Main Authors: Edwin Lasonder, Chris J Janse, Geert-Jan van Gemert, Gunnar R Mair, Adriaan M W Vermunt, Bruno G Douradinha, Vera van Noort, Martijn A Huynen, Adrian J F Luty, Hans Kroeze, Shahid M Khan, Robert W Sauerwein, Andrew P Waters, Matthias Mann, Hendrik G Stunnenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18974882/pdf/?tool=EBI