Expression of Hyaluronan Synthases (<it>HAS1–3</it>) and Hyaluronidases (<it>HYAL1–2</it>) in Serous Ovarian Carcinomas: Inverse Correlation between <it>HYAL1 </it>and Hyaluronan Content

<p>Abstract</p> <p>Background</p> <p>Hyaluronan, a tumor promoting extracellular matrix polysaccharide, is elevated in malignant epithelial ovarian tumors, and associates with an unfavorable prognosis. To explore possible contributors to the accumulation of hyaluronan,...

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Main Authors: Heikkinen Anna-Mari, Hämäläinen Kirsi, Tammi Raija H, Tammi Markku I, Sironen Reijo, Rilla Kirsi, Nykopp Timo K, Komulainen Marja, Kosma Veli-Matti, Anttila Maarit
Format: Article
Language:English
Published: BMC 2009-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/143