Antiparasitic Activity of Natural and Semi-Synthetic Tirucallane Triterpenoids from Schinus terebinthifolius (Anacardiaceae): Structure/Activity Relationships

Antiparasitic Activity of Natural and Semi-Synthetic Tirucallane Triterpenoids from Schinus terebinthifolius (Anacardiaceae): Structure/Activity Relationships

Leishmaniasis and Chagas are diseases caused by parasitic protozoans that affect the poorest population in the World, causing a high mortality and morbidity. As a result of highly toxic and long-term treatments, the discovery of novel, safe and more efficacious drugs is essential. In this work, the...

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Bibliographic Details
Main Authors: Thiago R. Morais, Thais A. da Costa-Silva, Andre G. Tempone, Samanta Etel T. Borborema, Marcus T. Scotti, Raquel Maria F. de Sousa, Ana Carolina C. Araujo, Alberto de Oliveira, Sérgio Antônio L. de Morais, Patricia Sartorelli, João Henrique G. Lago
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Molecules
Subjects:
Schinus terebinthifolius
leaves
tirucallane triterpenoids
Leishmania (L.) infantum
Trypanosoma cruzi
structure-activity
Online Access:http://www.mdpi.com/1420-3049/19/5/5761

Internet

http://www.mdpi.com/1420-3049/19/5/5761

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