Suppression of PKCδ/NF-κB Signaling and Apoptosis Induction through Extrinsic/Intrinsic Pathways Are Associated Magnolol-Inhibited Tumor Progression in Colorectal Cancer In Vitro and In Vivo

Suppression of PKCδ/NF-κB Signaling and Apoptosis Induction through Extrinsic/Intrinsic Pathways Are Associated Magnolol-Inhibited Tumor Progression in Colorectal Cancer In Vitro and In Vivo

Magnolol is one of the hydroxylated biphenyl compounds from the root and stem bark of <i>Magnolia officinalis</i>, which shown to possess anti-colorectal cancer (CRC) effects. However, the regulatory mechanism of magnolol on apoptosis and NF-κB signaling in human CRC has not been elucida...

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Bibliographic Details
Main Authors: Chun-Min Su, Yueh-Shan Weng, Lin-Yen Kuan, Jiann-Hwa Chen, Fei-Ting Hsu
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
PKCδ
NF-κB
magnolol
apoptosis
colorectal cancer
Online Access:https://www.mdpi.com/1422-0067/21/10/3527

Internet

https://www.mdpi.com/1422-0067/21/10/3527

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