Application of Cluster Analysis of Time Evolution for Magnetic Resonance Imaging -Derived Oxygen Extraction Fraction Mapping: A Promising Strategy for the Genetic Profile Prediction and Grading of Glioma

Application of Cluster Analysis of Time Evolution for Magnetic Resonance Imaging -Derived Oxygen Extraction Fraction Mapping: A Promising Strategy for the Genetic Profile Prediction and Grading of Glioma

Background: The intratumoral heterogeneity of oxygen metabolism and angiogenesis are core hallmarks of glioma, unveiling that genetic aberrations associated with magnetic resonance imaging (MRI) phenotypes may aid in the diagnosis and treatment of glioma.Objective: To explore the predictability of M...

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Bibliographic Details
Main Authors: Nanxi Shen, Shun Zhang, Junghun Cho, Shihui Li, Ju Zhang, Yan Xie, Yi Wang, Wenzhen Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Neuroscience
Subjects:
oxygen extraction fraction (OEF)
cluster analysis of time evolution
dynamic contrast-enhanced MRI (DCE-MRI)
multi-parameter MRI
isocitrate dehydrogenase (IDH)
O6-methylguanine-DNA methyltransferase (MGMT)
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.736891/full

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https://www.frontiersin.org/articles/10.3389/fnins.2021.736891/full

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