IL-1β is induced in reactive astrocytes in the somatosensory cortex of rats with genetic absence epilepsy at the onset of spike-and-wave discharges, and contributes to their occurrence

IL-1β is induced in reactive astrocytes in the somatosensory cortex of rats with genetic absence epilepsy at the onset of spike-and-wave discharges, and contributes to their occurrence

Interleukin (IL)-1β plays a crucial role in the mechanisms of limbic seizures in rodent models of temporal lobe epilepsy. We addressed whether activation of the IL-1β signaling occurs in rats with genetic absence epilepsy (GAERS) during the development of spike-and-wave discharges (SWDs). Moreover,...

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Bibliographic Details
Main Authors: Demet Akin, Teresa Ravizza, Mattia Maroso, Nihan Carcak, Tugba Eryigit, Ilaria Vanzulli, Rezzan Gülhan Aker, Annamaria Vezzani, Filiz Yılmaz Onat
Format: Article
Language:English
Published: Elsevier 2011-12-01
Series:Neurobiology of Disease
Subjects:
Inflammation
Absence seizures
Interleukins
SWD
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111001719

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http://www.sciencedirect.com/science/article/pii/S0969996111001719

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