Tuning a 96-Well Microtiter Plate Fluorescence-Based Assay to Identify AGE Inhibitors in Crude Plant Extracts

Tuning a 96-Well Microtiter Plate Fluorescence-Based Assay to Identify AGE Inhibitors in Crude Plant Extracts

Advanced glycation end-products (AGEs) are involved in the pathogenesis of numerous diseases. Among them, cellular accumulation of AGEs contributes to vascular complications in diabetes. Besides using drugs to lower blood sugar, a balanced diet and the intake of herbal products potentially limiting...

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Bibliographic Details
Main Authors: Luc Séro, Lionel Sanguinet, Patricia Blanchard, Bach Tai Dang, Sylvie Morel, Pascal Richomme, Denis Séraphin, Séverine Derbré
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Molecules
Subjects:
advanced glycation end-products
automation
fluorescence
natural products
pentosidine
plant extract screening
vesperlysines
Online Access:http://www.mdpi.com/1420-3049/18/11/14320

Internet

http://www.mdpi.com/1420-3049/18/11/14320

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