Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria

<p>Abstract</p> <p>Background</p> <p>Currently, population pharmacokinetic (PK) studies of anti-malarial drugs are designed primarily by the logistical and ethical constraints of taking blood samples from patients, and the statistical models that are fitted to the data...

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Bibliographic Details
Main Authors: Lindegardh Niklas, Tarning Joel, Duffull Stephen B, Jamsen Kris M, White Nicholas J, Simpson Julie A
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/10/1/181