Metformin Attenuates Postinfarction Myocardial Fibrosis and Inflammation in Mice

Metformin Attenuates Postinfarction Myocardial Fibrosis and Inflammation in Mice

Diabetes is a major risk factor for the development of cardiovascular disease with a higher incidence of myocardial infarction. This study explores the role of metformin, a first-line antihyperglycemic agent, in postinfarction fibrotic and inflammatory remodeling in mice. Three-month-old C57BI/6J mi...

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Bibliographic Details
Main Authors: Halyna Loi, Solomiia Kramar, Charlotte Laborde, Dimitri Marsal, Nathalie Pizzinat, Daniel Cussac, Jerome Roncalli, Frederic Boal, Helene Tronchere, Oleksandra Oleshchuk, Mykhaylo Korda, Oksana Kunduzova
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
metformin
myocardial infarction
fibrosis
inflammation
cardiac remodeling
Online Access:https://www.mdpi.com/1422-0067/22/17/9393

Internet

https://www.mdpi.com/1422-0067/22/17/9393

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