The Removal of Endo- and Enterotoxins From Bacteriophage Preparations

The production of phages for therapeutic purposes demands fast, efficient and scalable purification procedures. Phage lysates have a wide range of impurities, of which endotoxins of gram-negative bacteria and protein toxins produced by many pathogenic bacterial species are harmful to humans. The hig...

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Bibliographic Details
Main Authors: Ville Hietala, Jenni Horsma-Heikkinen, Annelie Carron, Mikael Skurnik, Saija Kiljunen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01674/full