VKORC1 and Novel CYP2C9 Variation Predict Warfarin Response in Alaska Native and American Indian People

VKORC1 and Novel CYP2C9 Variation Predict Warfarin Response in Alaska Native and American Indian People

Alaska Native and American Indian (AN/AI) people have unique pharmacogene variation that may affect warfarin disposition and therapeutic response. We performed targeted genotyping for cytochrome P450 (CYP)2C9, vitamin K epoxide oxidase reductase complex subunit 1 (VKORC1), CYP4F2, CYP4F11, and gamma...

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Bibliographic Details
Main Authors: Lindsay M. Henderson, Renee F. Robinson, Lily Ray, Burhan A. Khan, Tianran Li, Denise A. Dillard, Brian D. Schilling, Mike Mosley, Patricia L. Janssen, Alison E. Fohner, Allan E. Rettie, Kenneth E. Thummel, Timothy A. Thornton, David L. Veenstra
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12611

Internet

https://doi.org/10.1111/cts.12611

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