A Taxon-Specific and High-Throughput Method for Measuring Ligand Binding to Nicotinic Acetylcholine Receptors

A Taxon-Specific and High-Throughput Method for Measuring Ligand Binding to Nicotinic Acetylcholine Receptors

The binding of compounds to nicotinic acetylcholine receptors is of great interest in biomedical research. However, progress in this area is hampered by the lack of a high-throughput, cost-effective, and taxonomically flexible platform. Current methods are low-throughput, consume large quantities of...

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Bibliographic Details
Main Authors: Christina N. Zdenek, Richard J. Harris, Sanjaya Kuruppu, Nicholas J. Youngman, James S. Dobson, Jordan Debono, Muzaffar Khan, Ian Smith, Mike Yarski, David Harrich, Charlotte Sweeney, Nathan Dunstan, Luke Allen, Bryan G. Fry
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Toxins
Subjects:
venom
ligand
evolution
biosensor
nicotinic acetylcholine receptor
Online Access:https://www.mdpi.com/2072-6651/11/10/600

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https://www.mdpi.com/2072-6651/11/10/600

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