Paracrine effects of living human bone particles on the osteogenic differentiation of mesenchymal stem cells

Bone autografting remains the clinical model of choice for resolving problematic fractures. The precise mechanisms through which the autograft promotes bone healing are unknown. The present study examined the hypothesis that cells within the autograft secrete osteogenic factors promoting the differe...

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Bibliographic Details
Main Authors: A Atasoy-Zeybek, A Ivkovic, T Beyzadeoglu, A Ona, CH Evans, GT Kose
Format: Article
Language:English
Published: AO Research Institute Davos 2019-07-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/papers/vol038/pdf/v038a02.pdf