Integrative Analysis of Vaginal Microorganisms and Serum Metabolomics in Rats With Estrous Cycle Disorder Induced by Long-Term Heat Exposure Based on 16S rDNA Gene Sequencing and LC/MS-Based Metabolomics

Integrative Analysis of Vaginal Microorganisms and Serum Metabolomics in Rats With Estrous Cycle Disorder Induced by Long-Term Heat Exposure Based on 16S rDNA Gene Sequencing and LC/MS-Based Metabolomics

Long term heat exposure (HE) leads to estrous cycle disorder (ECD) in female rats and damages reproductive function. However, the regulation mechanism of vaginal microorganisms and serum metabolomics remains unclear. This study aimed to explore the effects of microbes on the vaginal secretions of ra...

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Bibliographic Details
Main Authors: GaiHong An, Yu Zhang, LiJun Fan, JiaJun Chen, MengFan Wei, Chao Li, XueWei Chen, Li Zhang, DanFeng Yang, Jing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
estrous cycle disorder
long-term heat exposure
neurotransmitter
serum metabolomics
vaginal microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.595716/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.595716/full

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