The effect of pneumococcal immunization on total and antigen-specific B cells in patients with severe chronic kidney disease

The effect of pneumococcal immunization on total and antigen-specific B cells in patients with severe chronic kidney disease

Abstract Background While the 23-valent pneumococcal polysaccharide vaccine (PPV23) is routinely used in Canada and some other countries to prevent pneumococcal infection in adults with chronic kidney disease (CKD), patients develop a suboptimal antibody response to PPV23 due to their immune dysfunc...

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Bibliographic Details
Main Authors: Gabrielle Nicole Gaultier, William McCready, Marina Ulanova
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Immunology
Subjects:
Chronic kidney disease (CKD)
Streptococcus pneumoniae
B cells
Memory B cells
T-cell independent response
T-cell dependent response
Online Access:http://link.springer.com/article/10.1186/s12865-019-0325-9

Internet

http://link.springer.com/article/10.1186/s12865-019-0325-9

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