High-dimensional analysis of intestinal immune cells during helminth infection

High-dimensional analysis of intestinal immune cells during helminth infection

Single cell isolation from helminth-infected murine intestines has been notoriously difficult, due to the strong anti-parasite type 2 immune responses that drive mucus production, tissue remodeling and immune cell infiltration. Through the systematic optimization of a standard intestinal digestion p...

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Bibliographic Details
Main Authors: Laura Ferrer-Font, Palak Mehta, Phoebe Harmos, Alfonso J Schmidt, Sally Chappell, Kylie M Price, Ian F Hermans, Franca Ronchese, Graham le Gros, Johannes U Mayer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-02-01
Series:eLife
Subjects:
H. polygyrus
type 2 immunity
intestinal immune cells
cell isolation
helminth infection
Online Access:https://elifesciences.org/articles/51678

Internet

https://elifesciences.org/articles/51678

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