Oral pre-treatment with thiocyanate (SCN−) protects against myocardial ischaemia–reperfusion injury in rats

Abstract Despite improvements in revascularization after a myocardial infarction, coronary disease remains a major contributor to global mortality. Neutrophil infiltration and activation contributes to tissue damage, via the release of myeloperoxidase (MPO) and formation of the damaging oxidant hypo...

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Bibliographic Details
Main Authors: Luke Hall, Chaouri Guo, Sarah Tandy, Kathryn Broadhouse, Anthony C. Dona, Ernst Malle, Emil D. Bartels, Christina Christoffersen, Stuart M. Grieve, Gemma Figtree, Clare L. Hawkins, Michael J. Davies
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92142-x