MiR-144 Inhibits Proliferation and Induces Apoptosis and Autophagy in Lung Cancer Cells by Targeting TIGAR

Background: MiRNAs are noncoding RNAs of 20-24 nucleotides that function as post-transcriptional negative regulators of gene expression. MiRNA genes are usually transcribed by RNA polymerase II in the nucleus. Their initial products are pre-miRNAs which have cap sequences and polyA tails. The p53-in...

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Bibliographic Details
Main Authors: Shanshan Chen, Ping Li, Juan Li, Yuanyuan Wang, Yuwen Du, Xiaonan Chen, Wenqiao Zang, Huaqi Wang, Heying Chu, Guoqiang Zhao, Guojun Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/369755