Impact of Pre-Analytical Factors on MSI Test Accuracy in Mucinous Colorectal Adenocarcinoma: A Multi-Assay Concordance Study

Impact of Pre-Analytical Factors on MSI Test Accuracy in Mucinous Colorectal Adenocarcinoma: A Multi-Assay Concordance Study

Immunohistochemistry (IHC) and polymerase chain reaction (PCR) and fragment separation by capillary electrophoresis represent the current clinical laboratory standard for the evaluation of microsatellite instability (MSI) status. The importance of reporting MSI status in colorectal cancer is based o...

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Bibliographic Details
Main Authors: Umberto Malapelle, Paola Parente, Francesco Pepe, Caterina De Luca, Pellegrino Cerino, Claudia Covelli, Mariangela Balestrieri, Gianluca Russo, Antonio Bonfitto, Pasquale Pisapia, Fabiola Fiordelisi, Maria D’Armiento, Dario Bruzzese, Fotios Loupakis, Filippo Pietrantonio, Maria Triassi, Matteo Fassan, Giancarlo Troncone, Paolo Graziano
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
predictive molecular pathology
IHC
fully automated RT—PCR
microfluidic
mCRC
Online Access:https://www.mdpi.com/2073-4409/9/9/2019

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https://www.mdpi.com/2073-4409/9/9/2019

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