Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease

Abstract Background Advanced age-related macular degeneration (AMD) is a leading cause of blindness. While around half of the genetic contribution to advanced AMD has been uncovered, little is known about the genetic architecture of early AMD. Methods To identify genetic factors for early AMD, we co...

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Bibliographic Details
Main Authors: Thomas W. Winkler, Felix Grassmann, Caroline Brandl, Christina Kiel, Felix Günther, Tobias Strunz, Lorraine Weidner, Martina E. Zimmermann, Christina A. Korb, Alicia Poplawski, Alexander K. Schuster, Martina Müller-Nurasyid, Annette Peters, Franziska G. Rauscher, Tobias Elze, Katrin Horn, Markus Scholz, Marisa Cañadas-Garre, Amy Jayne McKnight, Nicola Quinn, Ruth E. Hogg, Helmut Küchenhoff, Iris M. Heid, Klaus J. Stark, Bernhard H. F. Weber
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Medical Genomics
Subjects:
Genome-wide association study (GWAS)
Meta-analysis
Age-related macular degeneration (AMD)
Early AMD
CD46
TYR
Online Access:http://link.springer.com/article/10.1186/s12920-020-00760-7

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http://link.springer.com/article/10.1186/s12920-020-00760-7

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