Structure-based molecular simulations reveal the enhancement of biased Brownian motions in single-headed kinesin.

Kinesin is a family of molecular motors that move unidirectionally along microtubules (MT) using ATP hydrolysis free energy. In the family, the conventional two-headed kinesin was experimentally characterized to move unidirectionally through "walking" in a hand-over-hand fashion by coordin...

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Bibliographic Details
Main Authors: Ryo Kanada, Takeshi Kuwata, Hiroo Kenzaki, Shoji Takada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3572960?pdf=render