β-Naphthoflavone Activation of the Ah Receptor Alleviates Irradiation-Induced Intestinal Injury in Mice

β-Naphthoflavone Activation of the Ah Receptor Alleviates Irradiation-Induced Intestinal Injury in Mice

Radiotherapy induced gastrointestinal syndrome results from the acute damage of intestinal stem cells, impaired crypts reconstruction, and subsequent breakdown of the mucosal barrier. The toxicity of ionizing radiation is associated with oxidative stress in the intestinal epithelial cells (IECs). Mo...

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Bibliographic Details
Main Authors: Xiaoliang Zhou, Deguan Li, Wenqing Xu, Heng Zhang, Hao Wang, Gary H. Perdew
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
AHR
Ah receptor
β-naphthoflavone
oxidative stress
radioprotection
intestinal damage
Online Access:https://www.mdpi.com/2076-3921/9/12/1264

Internet

https://www.mdpi.com/2076-3921/9/12/1264

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