Dietary iron restriction leads to a reduction in hepatic fibrosis in a rat model of non-alcoholic steatohepatitis

Iron overload in the liver causes oxidative stress and inflammation, which result in organ dysfunction, making it a risk factor for non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma. We aimed to evaluate the effect of dietary iron restriction on disease progression in rats fed a chol...

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Bibliographic Details
Main Authors: Naomichi Abe, Takuma Tsuchida, Shin-Ichiro Yasuda, Kozo Oka
Format: Article
Language:English
Published: The Company of Biologists 2019-05-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/8/5/bio040519