Are Systemic Voriconazole and Caspofungin Ototoxic? An Experimental Study with Rats

Are Systemic Voriconazole and Caspofungin Ototoxic? An Experimental Study with Rats

ObjectivesTo determine whether systemic administration of voriconazole and caspofungin causes ototoxicity.MethodsThis study was conducted on 32 healthy male Wistar albino rats. The baseline auditory brainstem response (ABR) thresholds of all animals were obtained under general anesthesia. Then, the...

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Bibliographic Details
Main Authors: Emine Aydın, Filiz Aydoğan, Eren Taştan, Ayşe İriz, Gökhan Karaca, İlknur Haberal Can
Format: Article
Language:English
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2012-09-01
Series:Clinical and Experimental Otorhinolaryngology
Subjects:
Auditory brainstem responses
Ototoxicity
Otology
Caspofungin
Voriconazole
Online Access:http://www.e-ceo.org/upload/pdf/ceo-5-145.pdf

Internet

http://www.e-ceo.org/upload/pdf/ceo-5-145.pdf

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