Intracellular product recycling in high succinic acid producing yeast at low pH

Abstract Background The metabolic engineering of Saccharomyces cerevisiae for the production of succinic acid has progressed dramatically, and a series of high-producing hosts are available. At low cultivation pH and high titers, the product transport can become bidirectional, i.e. the acid is reent...

Full description

Bibliographic Details
Main Authors: S. Aljoscha Wahl, Cristina Bernal Martinez, Zheng Zhao, Walter M. van Gulik, Mickel L. A. Jansen
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-017-0702-0