Intracellular product recycling in high succinic acid producing yeast at low pH
Abstract Background The metabolic engineering of Saccharomyces cerevisiae for the production of succinic acid has progressed dramatically, and a series of high-producing hosts are available. At low cultivation pH and high titers, the product transport can become bidirectional, i.e. the acid is reent...
Main Authors: | S. Aljoscha Wahl, Cristina Bernal Martinez, Zheng Zhao, Walter M. van Gulik, Mickel L. A. Jansen |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-05-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12934-017-0702-0 |
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