Gene Expression Analysis in Four Dogs With Canine Pemphigus Clinical Subtypes Reveals B Cell Signatures and Immune Activation Pathways Similar to Human Disease

Gene Expression Analysis in Four Dogs With Canine Pemphigus Clinical Subtypes Reveals B Cell Signatures and Immune Activation Pathways Similar to Human Disease

Pemphigus is a group of autoimmune-mediated mucocutaneous blistering diseases characterized by acantholysis. Pemphigus has also been recognized in dogs and shares similar clinical characteristics and variants with human pemphigus. While relationships between human and canine pemphigus have been repo...

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Bibliographic Details
Main Authors: Haya S. Raef, Cesar Piedra-Mora, Neil B. Wong, Diana Junyue Ma, Clement N. David, Nicholas A. Robinson, Ramón M. Almela, Jillian M. Richmond
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Medicine
Subjects:
canine (dog)
pemphigus
autoimmune blistering diseases
gene expression
NanoString
cytokine
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.723982/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.723982/full

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