Cladribine Analogues via O6-(Benzotriazolyl) Derivatives of Guanine Nucleosides

Cladribine Analogues via O6-(Benzotriazolyl) Derivatives of Guanine Nucleosides

Cladribine, 2-chloro-2′-deoxyadenosine, is a highly efficacious, clinically used nucleoside for the treatment of hairy cell leukemia. It is also being evaluated against other lymphoid malignancies and has been a molecule of interest for well over half a century. In continuation of our interest in t...

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Bibliographic Details
Main Authors: Sakilam Satishkumar, Prasanna K. Vuram, Siva Subrahmanyam Relangi, Venkateshwarlu Gurram, Hong Zhou, Robert J. Kreitman, Michelle M. Martínez Montemayor, Lijia Yang, Muralidharan Kaliyaperumal, Somesh Sharma, Narender Pottabathini, Mahesh K. Lakshman
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Molecules
Subjects:
cladribine
nucleoside
guanosine
benzotriazole
(benzotriazol-1yl-oxy)-tris(dimethylamino)phosphonium hexafluorophosphate
BOP
Online Access:http://www.mdpi.com/1420-3049/20/10/18437

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http://www.mdpi.com/1420-3049/20/10/18437

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