Optimization of 5-fluorouracil solid-lipid nanoparticles: a preliminary study to treat colon cancer

<p>Solid lipid nanoparticle (SLNs) formulae were utilized for the release of 5-fluorouracil (5-FU) inside the colonic medium for local treatment of colon cancer. SLNs were prepared by double emulsion-solvent evaporation technique (w/o/w) using triglyceride esters, Dynasan&#8482; 114 or Dyn...

Full description

Bibliographic Details
Main Author: Alaa Eldeen B. Yassin, Md. Khalid Anwer, Hammam A. Mowafy, Ibrahim M. El-Bagory, Mohsen A. Bayomi, Ibrahim A. Alsarra
Format: Article
Language:English
Published: Ivyspring International Publisher 2010-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v07p0398.htm