Neutrophil depletion reduces edema formation and tissue loss following traumatic brain injury in mice

Neutrophil depletion reduces edema formation and tissue loss following traumatic brain injury in mice

<p>Abstract</p> <p>Background</p> <p>Brain edema as a result of secondary injury following traumatic brain injury (TBI) is a major clinical concern. Neutrophils are known to cause increased vascular permeability leading to edema formation in peripheral tissue, but their...

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Bibliographic Details
Main Authors: Kenne Ellinor, Erlandsson Anna, Lindbom Lennart, Hillered Lars, Clausen Fredrik
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Journal of Neuroinflammation
Subjects:
Neutrophil
traumatic brain injury
brain edema
controlled cortical impact
neuroprotection
blood-brain-barrier
cell death
microglia
neutrophil-depletion
mouse.
Online Access:http://www.jneuroinflammation.com/content/9/1/17

Internet

http://www.jneuroinflammation.com/content/9/1/17

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