A generalizable pre-clinical research approach for orphan disease therapy

A generalizable pre-clinical research approach for orphan disease therapy

<p><b>Abstract</b></p> <p>With the advent of next-generation DNA sequencing, the pace of inherited orphan disease gene identification has increased dramatically, a situation that will continue for at least the next several years. At present, the numbers of such identifi...

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Bibliographic Details
Main Authors: Beaulieu Chandree L, Samuels Mark E, Ekins Sean, McMaster Christopher R, Edwards Aled M, Krainer Adrian R, Hicks Geoffrey G, Frey Brendan J, Boycott Kym M, MacKenzie Alex E
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Orphan disease therapy
Preclinical drug development
Generalizable screening methods
Translational toolbox
Online Access:http://www.ojrd.com/content/7/1/39

Internet

http://www.ojrd.com/content/7/1/39

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