Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative networks

STDP is dependent on the timing of pre- and post-synaptic activity. Here, the authors describe a symmetric STDP induction rule at CA3-CA3 synapses, which induces LTP over a broad range of paring intervals. Modelling suggests that this STDP rule may enhance storage capacity and pattern completion in...

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Bibliographic Details
Main Authors: Rajiv K. Mishra, Sooyun Kim, Segundo J. Guzman, Peter Jonas
Format: Article
Language:English
Published: Nature Publishing Group 2016-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11552