ROS-Sensitive Nanoparticles Co-delivering Dexamethasone and CDMP-1 for the Treatment of Osteoarthritis Through Chondrogenic Differentiation Induction and Inflammation Inhibition

ROS-Sensitive Nanoparticles Co-delivering Dexamethasone and CDMP-1 for the Treatment of Osteoarthritis Through Chondrogenic Differentiation Induction and Inflammation Inhibition

Objective: Osteoarthritis (OA) is a common subtype of arthritis. To date, treatment of OA focuses primarily on alleviating pain and improving joint function. The lack of a vascular system within synovial joints and the rapid removal of agents due to synovial exchange hinder continuous delivery of OA...

Full description

Bibliographic Details
Main Authors: Xiaodong Wu, Pengpeng Li, Jian Cheng, Qiang Xu, Beiji Lu, Conghui Han, Weiling Huo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
osteoarthritis (OA)
reactive oxygen species (ROS)
nanomicelle
dexamethasone
cartilage-derivedmor-phogeneticprotein-1 (CDMP-1)
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.608150/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.608150/full

Similar Items