Phenotypic Characterization of LEA Rat: A New Rat Model of Nonobese Type 2 Diabetes

Animal models have provided important information for the genetics and pathophysiology of diabetes. Here we have established a novel, nonobese rat strain with spontaneous diabetes, Long-Evans Agouti (LEA) rat derived from Long-Evans (LE) strain. The incidence of diabetes in the males was 10% at 6 mo...

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Bibliographic Details
Main Authors: Tadashi Okamura, Xiang Yuan Pei, Ichiro Miyoshi, Yukiko Shimizu, Rieko Takanashi-Yanobu, Yasumasa Mototani, Takao Kanai, Jo Satoh, Noriko Kimura, Noriyuki Kasai
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2013/986462