Interleukin-18 and interleukin-18 Binding Protein

Interleukin-18 and interleukin-18 Binding Protein

Interleukin-18 (IL 18) is a member of the IL 1 family of cytokines. Increasing reports have expanded the role of IL 18 in mediating inflammation in animal models of disease using IL 18 deficient mice, neutralization of IL 18 or deficiency in the IL 18 receptor alpha chain. Similar to IL 1β, IL 18...

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Bibliographic Details
Main Authors: Charles eDinarello, Daniela eNovick, SooHun eKim, Gilles eKaplanski
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Immunology
Subjects:
Autoimmune Diseases
Inflammasomes
Inflammation
Interleukin-1
Macrophages
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00289/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00289/full

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