Identification of dual histone modification-binding protein interaction by combining mass spectrometry and isothermal titration calorimetric analysis
Histone posttranslational modifications (HPTMs) play important roles in eukaryotic transcriptional regulation. Recently, it has been suggested that combinatorial modification codes that comprise two or more HPTMs can recruit readers of HPTMs, performing complex regulation of gene expression. However...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-03-01
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Series: | Journal of Advanced Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S209012321930181X |