Reduced-Beclin1-Expressing Mice Infected with Zika-R103451 and Viral-Associated Pathology during Pregnancy

Reduced-Beclin1-Expressing Mice Infected with Zika-R103451 and Viral-Associated Pathology during Pregnancy

Here, we used a mouse model with defective autophagy to further decipher the role of autophagy in the infection and disease of Zika virus (ZIKV)-R103451. Hemizygous (<i>Becn1</i><sup>+/−</sup>) and wild-type (<i>Becn1</i><sup>+/+</sup>) pregnant mice w...

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Bibliographic Details
Main Authors: Mohan Kumar Muthu Karuppan, Chet Raj Ojha, Myosotys Rodriguez, Jessica Lapierre, M. Javad Aman, Fatah Kashanchi, Michal Toborek, Madhavan Nair, Nazira El-Hage
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Viruses
Subjects:
Zika virus
autophagy-defective mouse-model
Beclin1
microcephaly
inflammatory molecules
growth factor
Online Access:https://www.mdpi.com/1999-4915/12/6/608

Internet

https://www.mdpi.com/1999-4915/12/6/608

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