Increased expression of SNARE proteins and synaptotagmin IV in islets from pregnant rats and in vitro prolactin-treated neonatal islets

Increased expression of SNARE proteins and synaptotagmin IV in islets from pregnant rats and in vitro prolactin-treated neonatal islets

During pregnancy and the perinatal period of life, prolactin (PRL) and other lactogenic substances induce adaptation and maturation of the stimulus-secretion coupling system in pancreatic β-cells. Since the SNARE molecules, SNAP-25, syntaxin 1, VAMP-2, and synaptotagmins participate in insu...

Full description

Bibliographic Details
Main Authors: DANIEL A CUNHA, MARIA EC AMARAL, CAROLINA PF CARVALHO, CARLA B COLLARES-BUZATO, EVERARDO M CARNEIRO, ANTONIO C BOSCHERO
Format: Article
Language:English
Published: BMC 2006-01-01
Series:Biological Research
Subjects:
insulin
pancreatic islets
pregnant rats
prolactin
SNARE proteins
synaptotagmin
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000300016

Internet

http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000300016

Similar Items