Dopamine modulates insulin release and is involved in the survival of rat pancreatic beta cells.

The local synthesis of dopamine and its effects on insulin release have been described in isolated islets. Thus, it may be accepted that dopamine exerts an auto-paracrine regulation of insulin secretion from pancreatic beta cells. The aim of the present study is to analyze whether dopamine is a regu...

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Bibliographic Details
Main Authors: Maria Jose Garcia Barrado, Maria Carmen Iglesias Osma, Enrique J Blanco, Marta Carretero Hernández, Virginia Sánchez Robledo, Leonardo Catalano Iniesta, Sixto Carrero, Jose Carretero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4401745?pdf=render