Glaucoma-causing ADAMTS17 mutations are also reproducibly associated with height in two domestic dog breeds: selection for short stature may have contributed to increased prevalence of glaucoma

Glaucoma-causing ADAMTS17 mutations are also reproducibly associated with height in two domestic dog breeds: selection for short stature may have contributed to increased prevalence of glaucoma

Abstract Background In humans, ADAMTS17 mutations are known to cause Weill-Marchesani-like syndrome, which is characterised by lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. Breed-specific homozygous mutations in ADAMTS17 are associated with primary open angle glaucoma...

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Bibliographic Details
Main Authors: Emily C. Jeanes, James A. C. Oliver, Sally L. Ricketts, David J. Gould, Cathryn S. Mellersh
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Canine Genetics and Epidemiology
Subjects:
ADAMTS17
Height
Primary open angle Glaucoma
Primary Lens luxation
Weill-Marchesani-like syndrome
Online Access:http://link.springer.com/article/10.1186/s40575-019-0071-6

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http://link.springer.com/article/10.1186/s40575-019-0071-6

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