Chronic myeloid leukemia: an overview of the determinants of effectiveness and therapeutic response in the first decade of treatment with imatinib mesylate in a Brazilian hospital

Chronic myeloid leukemia: an overview of the determinants of effectiveness and therapeutic response in the first decade of treatment with imatinib mesylate in a Brazilian hospital

Background: In the last decade, there has been a revolution in chronic myeloid leukemia treatment with the introduction of tyrosine kinase inhibitors with imatinib mesylate becoming the frontline therapy. Objective: To evaluate the therapeutic efficacy of imatinib mesylate in treating chronic m...

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Bibliographic Details
Main Authors: Danielle Maria Camelo Cid, Silvia Maria Meira Magalhaes, Acy Telles de Souza Quixada, Rita Paiva Pereira Honorio, Paola Franssinetti Torres Ferreira Costa, Samuel Roosevelt Campos dos Reis, Selda Maria de Aguiar Carvalho, David Antonio Camelo Cid, Rafael Moura e Sucupira, Mariana Fatima Cabral de Oliveira
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Revista Brasileira de Hematologia e Hemoterapia
Subjects:
Leukemia, myelogenous, chronic, BCR-ABL positive/drug therapy
Protein-tyrosine kinases/therapeutic use
Piperazines/therapeutic use
Antineoplastic combined chemotherapy protocols/therapeutic use
Treatment outcome
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842013000600389&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842013000600389&lng=en&tlng=en

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