Rapid Generation of In Vitro Multicellular Spheroids for the Study of Monoclonal Antibody Therapy
<p>Tumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates and are difficult to study <i>in vitro</i>. Cells cultured as monolayers typically exhibit less resistance to therapy than those grown <i>in vivo. </i>Therefore, it...
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| Format: | Article |
| Language: | English |
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Ivyspring International Publisher
2011-01-01
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| Series: | Journal of Cancer |
| Online Access: | http://www.jcancer.org/v02p0507.htm |