Exhaustion of Protective Heat Shock Response Induces Significant Tumor Damage by Apoptosis after Modulated Electro-Hyperthermia Treatment of Triple Negative Breast Cancer Isografts in Mice

Exhaustion of Protective Heat Shock Response Induces Significant Tumor Damage by Apoptosis after Modulated Electro-Hyperthermia Treatment of Triple Negative Breast Cancer Isografts in Mice

Modulated electro-hyperthermia (mEHT) is a complementary antitumor therapy applying capacitive radiofrequency at 13.56 MHz. Here we tested the efficiency of mEHT treatment in a BALB/c mouse isograft model using the firefly luciferase-transfected triple-negative breast cancer cell line, 4T1. Tumors i...

Full description

Bibliographic Details
Main Authors: Lea Danics, Csaba András Schvarcz, Pedro Viana, Tamás Vancsik, Tibor Krenács, Zoltán Benyó, Tamás Kaucsár, Péter Hamar
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
modulated electro-hyperthermia (mEHT)
triple-negative breast cancer (TNBC)
isogenic mouse cancer
heat-shock protein-70
BALB/C mouse
Online Access:https://www.mdpi.com/2072-6694/12/9/2581

Internet

https://www.mdpi.com/2072-6694/12/9/2581

Similar Items