Identification of key pathways and genes in PTEN mutation prostate cancer by bioinformatics analysis

Identification of key pathways and genes in PTEN mutation prostate cancer by bioinformatics analysis

Abstract Background Prostate cancer (Pca) remains one of the leading adult malignancies. PTEN (Phosphatase and Tensin Homolog) mutant is the top common mutated genes in prostate cancer, which makes it a promising biomarker in future individualized treatment. Methods We obtained gene expression data...

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Bibliographic Details
Main Authors: Jian Sun, Shugen Li, Fei Wang, Caibin Fan, Jianqing Wang
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Medical Genetics
Subjects:
Prostate cancer
Bioinformatics analysis
PTEN mutation
TCGA
RNA seq
Online Access:https://doi.org/10.1186/s12881-019-0923-7

Internet

https://doi.org/10.1186/s12881-019-0923-7

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