Nanomechanics of multidomain neuronal cell adhesion protein contactin revealed by single molecule AFM and SMD

Nanomechanics of multidomain neuronal cell adhesion protein contactin revealed by single molecule AFM and SMD

Abstract Contactin-4 (CNTN4) is a complex cell adhesion molecule (CAM) localized at neuronal membranes, playing a key role in maintaining the mechanical integrity and signaling properties of the synapse. CNTN4 consists of six immunoglobulin C2 type (IgC2) domains and four fibronectin type III (FnIII...

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Bibliographic Details
Main Authors: Karolina Mikulska-Ruminska, Andrej J. Kulik, Carine Benadiba, Ivet Bahar, Giovanni Dietler, Wieslaw Nowak
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09482-w

Internet

https://doi.org/10.1038/s41598-017-09482-w

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